Implementation of the main chain directed assignment strategy. Computer assisted approach.

@article{Nelson1991ImplementationOT,
  title={Implementation of the main chain directed assignment strategy. Computer assisted approach.},
  author={Sarah J. Nelson and Diane M. Schneider and A Joshua Wand},
  journal={Biophysical journal},
  year={1991},
  volume={59 5},
  pages={1113-22}
}
A computer-assisted procedure has been developed to apply the main chain directed (MCD) assignment strategy to the analysis of 1H NMR spectra of proteins. The underlying mathematical foundation of this procedure, termed MCDPAT, is presented. MCDPAT is based upon the expanded library of MCD patterns defined previously (A.J. Wand and S.J. Nelson. 1991. Biophys. J. 59:1101-1112), and has been evaluated with both simulated and experimental data from the protein ubiquitin. The influence of the… CONTINUE READING

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