Implementation of functional genomics for gene discovery in alkaloid producing plants

  title={Implementation of functional genomics for gene discovery in alkaloid producing plants},
  author={Alain Goossens and Heiko Rischer},
  journal={Phytochemistry Reviews},
Two centuries after the discovery of the first alkaloids, many enzymes involved in plant alkaloid biosynthesis have been identified. Nevertheless, the biosynthetic pathways for most of the plant alkaloids still remain incompletely characterised and understanding the regulatory mechanisms controlling the onset and flux of alkaloid biosynthesis is virtually inexistent. This information is however crucial to allow modelling of metabolic networks and predictive metabolic engineering. In the… CONTINUE READING
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