Implementation of an evidence-based "standard operating procedure" and outcome in septic shock.

@article{Kortgen2006ImplementationOA,
  title={Implementation of an evidence-based "standard operating procedure" and outcome in septic shock.},
  author={Andreas Kortgen and Petra Niederpr{\"u}m and Michael Bauer},
  journal={Critical care medicine},
  year={2006},
  volume={34 4},
  pages={943-9}
}
OBJECTIVE To assess the impact of an algorithm defining resuscitation according to early goal-directed therapy, glycemic control, administration of stress doses of hydrocortisone, and use of recombinant human activated protein C (rhAPC) on measures of organ dysfunction and outcome in septic shock. DESIGN Retrospective cohort study. SETTING Multidisciplinary ten-bed intensive care unit of a university hospital. PATIENTS Sixty patients were analyzed: 30 consecutive patients fulfilling… CONTINUE READING