Implants for drug delivery to the posterior segment of the eye: a focus on stimuli-responsive and tunable release systems.

@article{Yasin2014ImplantsFD,
  title={Implants for drug delivery to the posterior segment of the eye: a focus on stimuli-responsive and tunable release systems.},
  author={Muhammad Naveed Yasin and Darren Svirskis and Ali Seyfoddin and Ilva D Rupenthal},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2014},
  volume={196},
  pages={208-21}
}
Efficient drug delivery to the posterior segment of the eye is a challenging task for the formulation scientist. Current treatment of chronic back-of-the-eye conditions requires frequent intravitreal injections of drug containing solutions due to the short half-life and limited tissue permeation of the administered molecules. Sustained release ocular delivery systems offering reduced administration frequencies have therefore gained popularity over recent years with a few implants already on the… CONTINUE READING