Implantation of healthy matrix-embedded endothelial cells rescues dysfunctional endothelium and ischaemic tissue in liver engraftment.

Abstract

OBJECTIVE Liver transplantation is limited by ischaemic injury which promotes endothelial cell and hepatocyte dysfunction and eventually organ failure. We sought to understand how endothelial state determines liver recovery after hepatectomy and engraftment. DESIGN Matrix-embedded endothelial cells (MEECs) with retained healthy phenotype or control… (More)
DOI: 10.1136/gutjnl-2015-310409

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