Implantable pumps for drug delivery to the brain

Abstract

This article reviews the role of implantable pumps in the treatment of CNS tumors. Systemic administration of chemotherapeutic agents has been associated with various problems, including adverse systemic effects and decreased concentration of the drug at the target site. Continuous infusion of chemotherapeutic agents with implantble pumps have been used in an attempt to overcome these problems. Various different chemo-therapeutic agents have been used for this purpose, and catheters have been placed in the intraspinal, intraventricular and intratumoral locations.

DOI: 10.1007/BF01060219

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@article{Bakhshi1995ImplantablePF, title={Implantable pumps for drug delivery to the brain}, author={Sanjay Bakhshi and Richard B. North}, journal={Journal of Neuro-Oncology}, year={1995}, volume={26}, pages={133-139} }