Impedance measurement for real time detection of neuronal cell death.

  title={Impedance measurement for real time detection of neuronal cell death.},
  author={Sebastian Diemert and Amalia M. Dolga and Svenja Tobaben and Julia Grohm and Susan Ohlsson Pfeifer and E Oexler and Carsten Culmsee},
  journal={Journal of neuroscience methods},
  volume={203 1},
Detection of neuronal cell death is a standard requirement in cell culture models of neurodegenerative diseases. Although plenty of viability assays are available for in vitro applications, most of these are endpoint measurements providing only little information on the kinetics of cell death. Here, we validated the xCELLigence system based on impedance measurement for real-time detection of cell death in a neuronal cell line of immortalized hippocampal neurons (HT-22 cells), neuronal… CONTINUE READING
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