Impairment of the activity of the plasma membrane Ca²⁺-ATPase in Alzheimer's disease.

Abstract

AD (Alzheimer's disease) is an age-associated neurodegenerative disorder where the accumulation of neurotoxic Aβ (amyloid β-peptide) in senile plaques is a typical feature. Recent studies point out a relationship between Aβ neurotoxicity and Ca2+ dyshomoeostasis, but the molecular mechanisms involved are still under discussion. The PMCAs (plasma membrane… (More)
DOI: 10.1042/BST0390819

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Cite this paper

@article{Mata2011ImpairmentOT, title={Impairment of the activity of the plasma membrane Ca²⁺-ATPase in Alzheimer's disease.}, author={Ana Teresa Mata and Mar{\'i}a Cruz Berrocal and Maria Rosario Sep{\'u}lveda}, journal={Biochemical Society transactions}, year={2011}, volume={39 3}, pages={819-22} }