Impairment of systemic concomitant antitumor immunity by excess soluble tumor antigen

Abstract

Animals bearing a 3-methylcholanthrene induced sarcoma called MC1 rejected substantial numbers of a suspension of the same tumor cells injected IV in comparison with normal rats. The factors that protected the host against lung metastases were impaired by the administration of tumor antigen in the form of irradiated tumor cells or soluble tumor antigen… (More)
DOI: 10.1007/BF00205662

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