Impairment of social and moral behavior related to early damage in human prefrontal cortex

@article{Anderson1999ImpairmentOS,
  title={Impairment of social and moral behavior related to early damage in human prefrontal cortex},
  author={Steven W. Anderson and Antoine Bechara and Hanna Damasio and Daniel Tranel and Antonio R. Damasio},
  journal={Nature Neuroscience},
  year={1999},
  volume={2},
  pages={1032-1037}
}
The long-term consequences of early prefrontal cortex lesions occurring before 16 months were investigated in two adults. As is the case when such damage occurs in adulthood, the two early-onset patients had severely impaired social behavior despite normal basic cognitive abilities, and showed insensitivity to future consequences of decisions, defective autonomic responses to punishment contingencies and failure to respond to behavioral interventions. Unlike adult-onset patients, however, the… 
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