Impairment of nesting behaviour in 3xTg-AD mice.

@article{TorresLista2013ImpairmentON,
  title={Impairment of nesting behaviour in 3xTg-AD mice.},
  author={Virginia Torres-Lista and Lydia Gim{\'e}nez-Llort},
  journal={Behavioural brain research},
  year={2013},
  volume={247},
  pages={153-7}
}
Deterioration in executive functions and daily life activities (DLA) are early signs of Alzheimer's disease (AD) that signal the need for caregiver attention. We have addressed this issue in the 3xTg-AD mice model for AD and studied nesting behaviour as a natural DLA of parental structures as well as at early- (6 month-old) and advanced-stages (12 month-old) of the disease in isolated animals. The results show genetic, gender and age-dependent impairment of nesting behaviour but also aware… CONTINUE READING

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