Impairment of intracerebral arteriole dilation responses after subarachnoid hemorrhage. Laboratory investigation.

@article{Park2009ImpairmentOI,
  title={Impairment of intracerebral arteriole dilation responses after subarachnoid hemorrhage. Laboratory investigation.},
  author={Ik-Seong Park and Joseph R. Meno and Cordelie E. Witt and Abhineet M. Chowdhary and Thien-son K Nguyen and H. Richard Winn and A. C. H. Ngai and Gavin W. Britz},
  journal={Journal of neurosurgery},
  year={2009},
  volume={111 5},
  pages={
          1008-13
        }
}
OBJECT Cerebrovascular dysfunction after subarachnoid hemorrhage (SAH) may contribute to ischemia, but little is known about the contribution of intracerebral arterioles. In this study, the authors tested the hypothesis that SAH inhibits the vascular reactivity of intracerebral arterioles and documented the time course of this dysfunction. METHODS Subarachnoid hemorrhage was induced using an endovascular filament model in halothane-anesthetized male Sprague-Dawley rats. Penetrating… CONTINUE READING
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