Impairment of hormone dependent signal transfer by chronic SSPE virus infection.

Abstract

In a CNS-derived cell line, the cellular response to hormonal stimulation, represented by the rise of intracellular cAMP levels, is impaired under the influence of a persisting neurotropic virus infection. This dysfunction is caused by the decrease in adenylate cyclase activity, most probably due to the virus-induced loss of active catalytic units. 

Topics

Cite this paper

@article{Halbach1979ImpairmentOH, title={Impairment of hormone dependent signal transfer by chronic SSPE virus infection.}, author={Maurits Halbach and K P Koschel}, journal={The Journal of general virology}, year={1979}, volume={42 3}, pages={615-9} }