Impairment of bone mass development in children with chronic cholestatic liver disease.

@article{Taveira2007ImpairmentOB,
  title={Impairment of bone mass development in children with chronic cholestatic liver disease.},
  author={Adriana T{\'a}vora de Albuquerque Taveira and Maria Inez Machado Fernandes and L{\'i}via C{\^a}mara de Carvalho Galv{\~a}o and Regina Sawamura and Enaldo de Mello Vieira and Francisco Jos{\'e} Albuquerque de Paula},
  journal={Clinical endocrinology},
  year={2007},
  volume={66 4},
  pages={
          518-23
        }
}
OBJECTIVE To analyse aspects of mineral metabolism, bone mineral density (BMD), bone remodelling activity and serum IGF-1 levels in children with chronic cholestatic disease (CCLD). PATIENTS AND MEASUREMENTS A total of 13 children with chronic cholestatic liver disease (CCLD; mean age 7.2 +/- 4.8 years) and 22 control subjects (mean age 7.6 +/- 4.5 years) were studied. Serum osteocalcin, bone alkaline phosphatase (BAP), 25-hydroxyvitamin D, PTH and IGF-1 levels and urinary deoxypyridinoline… CONTINUE READING

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