Impairment of alternate pathway (CD2) of T cell activation in leprosy

Abstract

Recent studies in basic immunology have been directed towards the understanding of the mechanism of T cell activation. T cells can be activated to proliferatevia the classical pathway through the antigen receptor (CD3-Ti) orvia the alternate pathway through the CD2 receptor. Since immunologic unresponsiveness in lepromatous leprosy is considered to be due… (More)
DOI: 10.1007/BF02703519

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