Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat

@article{Forster1994ImpairmentOA,
  title={Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat is prevented by tolrestat},
  author={H. G. Forster and Piet M. ter Wee and Thomas C. Hohman and Murray Epstein},
  journal={Diabetologia},
  year={1994},
  volume={39},
  pages={907-914}
}
By permitting the separation of increased aldose reductase activity from hyperglycaemia and insulin deficiency, galactose-fed rats have constituted a useful model for investigating diabetic complications. Such rats manifest an impaired afferent arteriolar responsiveness to pressure similar to that of rats 4 to 6 weeks after induction of diabetes with… CONTINUE READING