Impairment in the cognitive functioning of men with fragile X-associated tremor/ataxia syndrome (FXTAS)

@article{Grigsby2006ImpairmentIT,
  title={Impairment in the cognitive functioning of men with fragile X-associated tremor/ataxia syndrome (FXTAS)},
  author={Jim Grigsby and Angela G. Brega and S{\'e}bastien Jacquemont and Danuta Z Loesch and Paul J. Hagerman},
  journal={Journal of the Neurological Sciences},
  year={2006},
  volume={248},
  pages={227-233}
}
Disorders associated with fragile X syndrome involve a trinucleotide (CGG) repeat expansion in the FMR1 gene. Recently, a progressive movement disorder (fragile X-associated tremor/ataxia syndrome [FXTAS]) has been identified in premutation carriers, persons with 55 to 200 CGG repeats. In addition to ataxia, action tremor, and Parkinsonism, early case reports suggested that FXTAS involves impaired cognition, but the precise nature of the impairment has not been elucidated. In this first… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

Similar Papers

Loading similar papers…