Impaired thermoregulation against cold in capsaicin pretreated rats

  title={Impaired thermoregulation against cold in capsaicin pretreated rats},
  author={Gyorgy Benedek and Margit Szikszay and Ferenc Obál},
  journal={Pfl{\"u}gers Archiv},
A study was made of the effects of pretreatment with fractionated capsaicin on the changes in body temperature (Tb) induced in rats by exposure to cold and to warm environments, and by administration of histamine (40 mg·kg−1) or of pentobarbital (20 mg·kg−1) At the ambient temperature of 22 °C the Tb of capsaicin pretreated rats was lower than that of rats treated only with solvent (p<0.001). The capsaicin pretreated rats showed impairment of thermoregulation at both high and low environmental… 

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