Impaired spatial selectivity and intact phase precession in two-dimensional virtual reality

  title={Impaired spatial selectivity and intact phase precession in two-dimensional virtual reality},
  author={Zahra M. Aghajan and Lavanya Acharya and Jason J Moore and Jesse D. Cushman and Cliff Vuong and M. Mehta},
  journal={Nature Neuroscience},
  • Zahra M. Aghajan, Lavanya Acharya, +3 authors M. Mehta
  • Published 2015
  • Computer Science, Medicine
  • Nature Neuroscience
  • During real-world (RW) exploration, rodent hippocampal activity shows robust spatial selectivity, which is hypothesized to be governed largely by distal visual cues, although other sensory-motor cues also contribute. Indeed, hippocampal spatial selectivity is weak in primate and human studies that use only visual cues. To determine the contribution of distal visual cues only, we measured hippocampal activity from body-fixed rodents exploring a two-dimensional virtual reality (VR). Compared to… CONTINUE READING
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