Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load.

@article{He2009ImpairedSE,
  title={Impaired small-world efficiency in structural cortical networks in multiple sclerosis associated with white matter lesion load.},
  author={Yong He and Alain Dagher and Zhang Chen and Arnaud Charil and Alex P. Zijdenbos and Keith J. Worsley and Alan C. Evans},
  journal={Brain : a journal of neurology},
  year={2009},
  volume={132 Pt 12},
  pages={3366-79}
}
White matter tracts, which play a crucial role in the coordination of information flow between different regions of grey matter, are particularly vulnerable to multiple sclerosis. Many studies have shown that the white matter lesions in multiple sclerosis are associated with focal abnormalities of grey matter, but little is known about the alterations in the coordinated patterns of cortical morphology among regions in the disease. Here, we used cortical thickness measurements from structural… CONTINUE READING
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