Impaired sexual behavior in male mice deficient for the beta1-3 N-acetylglucosaminyltransferase-I gene.

@article{Biellmann2008ImpairedSB,
  title={Impaired sexual behavior in male mice deficient for the beta1-3 N-acetylglucosaminyltransferase-I gene.},
  author={Franziska Biellmann and Timothy R. Henion and Kurt H. B{\"u}rki and Thierry Hennet},
  journal={Molecular reproduction and development},
  year={2008},
  volume={75 5},
  pages={699-706}
}
The beta1-3 N-acetylglucosaminyltransferase-1 (B3gnt1) gene encodes a poly-N-acetyllactosamine synthase which can initiate and extend poly-N-acetyllactosamine chains [Gal(beta1-4)GlcNAc (beta1-3)(n)]. Previous investigations with heterozygous and homozygous null mice for this gene have revealed the importance of poly-N-acetyllactosamine chains for the formation of olfactory axon connections with the olfactory bulb and the migration of gonadotropin releasing hormone neurons to the hypothalamus… CONTINUE READING
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