Impaired secretion of growth hormone-releasing hormone, growth hormone and IGF-I in elderly men.

@article{Bando1991ImpairedSO,
  title={Impaired secretion of growth hormone-releasing hormone, growth hormone and IGF-I in elderly men.},
  author={Hajime Bando and Chen Yu Zhang and Yoichi Takada and Rie Yamasaki and Shiro Saito},
  journal={Acta endocrinologica},
  year={1991},
  volume={124 1},
  pages={31-6}
}
The GHRH test and L-dopa test were performed in 12 normal young men (24.1 +/- 1.1 years) and 12 normal elderly men (77.8 +/- 1.4 years) to investigate age-related changes in secretion of GHRH, GH and IGF-I. The basal plasma levels of GHRH and GH were not significantly different in young and elderly men, but the basal plasma level of IGF-I was higher in the young men (159.0 +/- 11.7 vs 86.7 +/- 11.6 micrograms/l). The area under the curve for plasma GH in the GHRH test was less in the elderly… CONTINUE READING

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