Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats.

@article{Yefimova2002ImpairedRI,
  title={Impaired retinal iron homeostasis associated with defective phagocytosis in Royal College of Surgeons rats.},
  author={Marina G. Yefimova and J Jeanny and Nicole Keller and Claire Sergeant and Xavier Guillonneau and Carole Beaumont and Yves Courtois},
  journal={Investigative ophthalmology & visual science},
  year={2002},
  volume={43 2},
  pages={537-45}
}
PURPOSE To determine whether iron homeostasis disorder accompanies retinal degeneration in Royal College of Surgeons (RCS) rats. METHODS The presence of iron was revealed directly by proton-induced X-ray emission (PIXE) and indirectly by electron microscopy (EM). Ferritin, transferrin (Tf), and transferrin receptor (Tf-R) were localized by… CONTINUE READING