Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3.

@article{Stitt2005ImpairedRA,
  title={Impaired retinal angiogenesis in diabetes: role of advanced glycation end products and galectin-3.},
  author={Alan W. Stitt and Ciara McGoldrick and Aine Rice-McCaldin and David R. McCance and Josephine V. Glenn and Daniel Kaiyuan Hsu and Fu-tong Liu and Suzanne R. Thorpe and Tom A. Gardiner},
  journal={Diabetes},
  year={2005},
  volume={54 3},
  pages={785-94}
}
Suppression of angiogenesis during diabetes is a recognized phenomenon but is less appreciated within the context of diabetic retinopathy. The current study has investigated regulation of retinal angiogenesis by diabetic serum and determined if advanced glycation end products (AGEs) could modulate this response, possibly via AGE-receptor interactions. A… CONTINUE READING