Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait

@article{Hausdorff2003ImpairedRO,
  title={Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait},
  author={J. Hausdorff and J. Schaafsma and Y. Balash and A. Bartels and T. Gurevich and Nir Giladi},
  journal={Experimental Brain Research},
  year={2003},
  volume={149},
  pages={187-194}
}
Patients with Parkinson's disease (PD) often experience freezing of gait, a debilitating phenomenon during which the subject suddenly becomes unable to start walking or to continue to move forward. Little is known about the gait of those subjects with PD who experience freezing of gait or the pathophysiology of freezing. One possibility is that freezing of gait is a truly paroxysmal phenomenon and that the usual walking pattern of subjects who experience freezing of gait is not different than… Expand

Paper Mentions

Interventional Clinical Trial
The aim of study is to analyze the effects of different physical therapies (Aquatic Jogging, Neurofunctional Physiotherapy, Pilates Training and Nordic Walking) and Dance and compare… Expand
ConditionsParkinson Disease, Parkinson Disease 10
InterventionOther
Interventional Clinical Trial
Sample Size N= 10 Parkinson's disease patients with self-reported freezing of gait and 10 without self-reported freezing of gait (in total, 20 Parkinson's disease patients… Expand
ConditionsFreezing of Gait, Parkinson Disease
InterventionOther
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The findings could support the hypothesis that the freezing in ON is not a sudden phenomenon, as it could seem to the clinical observation, but it is rather compatible to a progressive disorganization in the gait planning, that can be initially compensated by an adaptation of the motor control. Expand
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Results suggest asymmetry and decreased coordination of gait are affected by step length and may not be factors in determining freezing ofgait in Parkinson's disease. Expand
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TLDR
PD subjects with FOG had increased variability in foot strike suggesting that in addition to stride length variability, foot strike variability could contribute to imbalance leading to falls. Expand
The role of gait rhythmicity and bilateral coordination of stepping in the pathophysiology of freezing of gait in Parkinson's disease
TLDR
It is proposed that impairments in the ongoing regulation of gait, even during periods in which freezing is not present, set the stage for the occurrence of a FOG episode. Expand
Noisy Interlimb Coordination Can Be a Main Cause of Freezing of Gait in Patients with Little to No Parkinsonism
TLDR
Compared gait patterns during straight walking between 9 patients with freezing of gait but little to no parkinsonism and 11 patients with Parkinson’s disease suggest that noisy interlimb coordination can affect regulation of the gait cycle. Expand
Is Freezing of Gait in Parkinson's Disease a Result of Multiple Gait Impairments? Implications for Treatment
TLDR
This work proposes distinct categories of interventions which aim to maintain a good level of locomotion control especially with respect to aspects related to FOG; and those that merely aim to escape from FOG once it occurs. Expand
Walking patterns in Parkinson's disease with and without freezing of gait
TLDR
It is concluded that parkinsonian gait-regardless of FOG-is irregular, not only in the legs, but also with respect to interlimb coordination between the arms and legs. Expand
Does freezing in Parkinson’s disease change limb coordination?
TLDR
The side of the body where gait terminated before freezing was in most cases the side of symptom-dominance, but not consistently so, and body side differences were larger than sequential deterioration of consecutive steps within each side. Expand
Freezing during tapping tasks in patients with advanced Parkinson’s disease and freezing of gait
TLDR
Although freezing of the lower limbs was easily assessed during an MDS-UPDRS task with a metronome, it was not correlated with the severity of freezing of gait (as evaluated during a standardized gait trajectory). Expand
What Can We Learn From Freezing of Gait in Parkinson’s Disease?
TLDR
It is possible that FOG in PD represents the ultimate break in the frontal lobe–basal ganglia–cerebellar–brainstem network that controls gait, and likely is the primary and continuous abnormality of “the gait network” in PD. Expand
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TLDR
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TLDR
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