Impaired radial artery compliance in normotensive subjects with familial hypercholesterolemia.

  title={Impaired radial artery compliance in normotensive subjects with familial hypercholesterolemia.},
  author={Cristina Giannattasio and Arduino Aleksander Mangoni and Monica Failla and Stefano Carugo and Maria Luisa Stella and P Stefanoni and Guido Grassi and Carlo Vergani and Giuseppe Mancia},
  volume={124 2},
Hypercholesterolemia impairs arteriolar dilatation, but whether the vascular abnormalities accompanying this condition include large artery function is unknown. We addressed this issue in 13 normotensive subjects with familial hypercholesterolemia (serum cholesterol 401.6 +/- 16.9 mg/dl, mean +/- S.E., FHC) and no evidence of atherosclerotic lesions, in whom radial artery (RA) diameter and blood pressure (BP) were measured beat to beat by an echotracking and a Finapres device, respectively. RA… CONTINUE READING


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