Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state.

@article{Ji2001ImpairedPO,
  title={Impaired production of naive T lymphocytes in human T-cell leukemia virus type I-infected individuals: its implications in the immunodeficient state.},
  author={Yasunaga Ji and Toshiyuki Sakai and Kisato Nosaka and Etoh Ki and Shiho Tamiya and Shin Koga and Shin-ichiro Mita and Makoto Uchino and Hiroaki Mitsuya and Masao Matsuoka},
  journal={Blood},
  year={2001},
  volume={97 10},
  pages={3177-83}
}
Opportunistic infections frequently occur in patients with adult T-cell leukemia (ATL) and human T-cell leukemia virus type I (HTLV-I) carriers. However, the underlying mechanisms of such infections remain unknown. To clarify the mechanism of immunodeficiency in those infected with HTLV-I, this study analyzed the T-cell subsets in HTLV-I carriers and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis and ATL using 3-color fluorescence with CD62L and CD45RA coexpression… CONTINUE READING
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