Impaired prefrontal cortical function and disrupted adaptive cognitive control in methamphetamine abusers: a functional magnetic resonance imaging study.

@article{Salo2009ImpairedPC,
  title={Impaired prefrontal cortical function and disrupted adaptive cognitive control in methamphetamine abusers: a functional magnetic resonance imaging study.},
  author={R. C. Salo and Stefan Ursu and Michael H. Buonocore and Martin H. Leamon and Cameron S. Carter},
  journal={Biological psychiatry},
  year={2009},
  volume={65 8},
  pages={706-9}
}
BACKGROUND Methamphetamine (MA) abuse is associated with neurotoxicity to frontostriatal brain regions with deleterious effects on cognitive processes. Deficits in behavioral control are thought to be one contributing factor to the sustainment of addictive behaviors in MA abuse. METHODS In order to examine patterns of behavioral control relevant to addiction, we employed a fast-event-related functional magnetic resonance imaging design to examine trial-to-trial reaction time (RT) adjustments… CONTINUE READING