Impaired osteogenic differentiation associated with connexin43/microRNA-206 in steroid-induced avascular necrosis of the femoral head.

@article{Liu2016ImpairedOD,
  title={Impaired osteogenic differentiation associated with connexin43/microRNA-206 in steroid-induced avascular necrosis of the femoral head.},
  author={Gang Liu and Gaobin Luo and Zhandong Bo and Xiaonan Liang and Jie Huang and Donghui Li},
  journal={Experimental and molecular pathology},
  year={2016},
  volume={101 1},
  pages={89-99}
}
Connexin(Cx)43 and microRNA(miR)-206 play an important role in osteogenesis. However, their role in steroid-induced femoral head osteonecrosis (SANFH) is still ambiguous. The present study aimed to establish a rabbit model and investigate osteogenesis in steroid-induced femoral head osteonecrosis occurring via Cx43/miR-206 and the changes of Wnt/β-catenin signal pathway-related proteins. A total of 72 adult New Zealand white rabbits were divided randomly into a model group (Group A) and a… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 39 references

Enoxaparin prevents steroid-related avascular necrosis of the femoral head

  • R Beckmann
  • ScientificWorldJournal
  • 2014

Expression profile of osteoprotegerin. RANK and RANKL genes in the femoral head of patients with avascular necrosis

  • S Samara
  • Exp. Mol. Pathol
  • 2014

Acute effects of glucocorticoids on serummarkers of osteoclasts, osteoblasts, and osteocytes

  • K BrabnikovaMaresova
  • Calcif. Tissue Int
  • 2013

Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling

  • S Mureli
  • Am. J. Physiol. Heart Circ. Physiol
  • 2013

Wnt / beta - catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

  • R. Zhang
  • 2013

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