Impaired neurogenesis in adult type-2 diabetic rats.

  title={Impaired neurogenesis in adult type-2 diabetic rats.},
  author={Bradley Lang and Yiping Yan and Robert J Dempsey and Raghu Vemuganti},
  journal={Brain research},
Type-2 diabetes is an adult onset condition that affects millions of people worldwide. The ensuing hyperglycemia renders multiple organs to various complications and increases the risk of learning and memory impairment. The Goto-Kakizaki (GK) rat developed from normoglycemic Wistar-Kyoto (WKY) rat is a model for type-2 diabetes, with insulin resistance developing around 12 weeks of age. We presently analyzed the neural progenitor proliferation and survival of the newly generated cells in the… CONTINUE READING


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