Impaired nerve growth factor homeostasis in patients with bipolar disorder

  title={Impaired nerve growth factor homeostasis in patients with bipolar disorder},
  author={I. Barbosa and R. B. Huguet and F. Neves and H. Reis and M. Bauer and Z. Janka and A. Palot{\'a}s and A. Teixeira},
  journal={The World Journal of Biological Psychiatry},
  pages={228 - 232}
  • I. Barbosa, R. B. Huguet, +5 authors A. Teixeira
  • Published 2011
  • Psychology, Medicine
  • The World Journal of Biological Psychiatry
  • Abstract Objective. Neuro-trophins are critically involved in neuro-plasticity, the impairment of which is a major role-player in bipolar disorder (BD), and their altered levels have been recently advocated in the patho-physiology of this affective malady. The aim of this study, therefore, was to evaluate the plasma levels of nerve growth factor (NGF) in BD patients in comparison with control subjects. Methods. Forty-nine BD type-I individuals (30 in mania and 19 in euthymia) and 36 healthy… CONTINUE READING
    54 Citations
    Circulating levels of GDNF in bipolar disorder
    • 55
    Neurotrophic factors in bipolar disorders patients with manic episode
    • PDF
    Nerve growth factor variations in patients with mood disorders: no changes in eight weeks of clinical treatment
    • 10
    • PDF
    Peripheral blood nerve growth factor levels in major psychiatric disorders.
    • 15
    • Highly Influenced
    The role of neurotrophins in bipolar disorder
    • G. Scola, A. Andreazza
    • Biology, Medicine
    • Progress in Neuro-Psychopharmacology and Biological Psychiatry
    • 2015
    • 30
    High insulin-like growth factor-1 in patients with bipolar I disorder: a trait marker?
    • 30
    Elevated serum levels of FGF-2, NGF and IGF-1 in patients with manic episode of bipolar disorder
    • 40
    Elevated Brain-Derived Neurotrophic Factor Correlates Negatively with Severity and Duration of Major Depressive Episodes
    • 21


    Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder
    • 159
    • PDF
    Reduced cerebrospinal fluid and plasma nerve growth factor in drug-naïve psychotic patients
    • 29
    Psychiatric vulnerability: Suggestions from animal models and role of neurotrophins
    • 78
    • Highly Influential
    The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease.
    • S. Counts, E. Mufson
    • Biology, Medicine
    • Journal of neuropathology and experimental neurology
    • 2005
    • 176
    • PDF
    Identifying and treating cognitive impairment in bipolar disorder.
    • 156