Impaired negative chronotropic response to adenosine in patients with inappropriate sinus tachycardia.

Abstract

INTRODUCTION Adenosine is an endogenous nucleoside that has an important role in the diagnosis and treatment of several cardiac arrhythmias. However, its effects on inappropriate sinus tachycardia (IST) are not well established. METHODS AND RESULTS In this study, the response to intravenous adenosine (0.1 to 0.15 mg/kg) was studied in 18 patients (age 46… (More)

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