Impaired movement control in Alzheimer's disease

@article{Ghilardi1999ImpairedMC,
  title={Impaired movement control in Alzheimer's disease},
  author={M. -Felice Ghilardi and Margherita Alberoni and Sabrina Marelli and Marina Soares Rossi and Ferruccio Fazio},
  journal={Neuroscience Letters},
  year={1999},
  volume={260},
  pages={45-48}
}
Movement accuracy in normal subjects depends on feedforward commands based on representation in memory of spatial and biomechanical features. Here we ask whether memory deficits in Alzheimer's disease (AD) interfere with movement planning and execution. Nine AD patients and nine age-matched controls moved a cursor to targets without seeing their limb. Starting and target positions were always visible on a screen, while, during movement, cursor position was either visible or blanked. Patients… CONTINUE READING
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