Impaired migration signaling in the hippocampus following prenatal hypoxia

@article{Golan2009ImpairedMS,
  title={Impaired migration signaling in the hippocampus following prenatal hypoxia},
  author={Maya Golan and Revital Mane and Gabriela Molczadzki and Michal Zuckerman and J. Regino Perez-polo},
  journal={Neuropharmacology},
  year={2009},
  volume={57},
  pages={511-522}
}
Prenatal hypoxia ischemia is a major cause of neurodevelopmental impairment in the newborn, associated with risk for motor, behavioral and cognitive impaired outcomes. We used an established mouse model of maternal hypoxia to examine the immediate molecular responses of signaling pathways associated with both cell death and neurogenesis. We also characterized responses to maternal pre-treatment with MgSO(4). Maternal hypoxia at embryonic day 17 (E17) failed to trigger inflammation or cell death… CONTINUE READING

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