Impaired microvascular function in normal children: effects of adiposity and poor glucose handling.

@article{Khan2003ImpairedMF,
  title={Impaired microvascular function in normal children: effects of adiposity and poor glucose handling.},
  author={Faisel Khan and Fiona C Green and J Stewart Forsyth and Stephen Greene and Andrew D. Morris and Jill J. F. Belch},
  journal={The Journal of physiology},
  year={2003},
  volume={551 Pt 2},
  pages={705-11}
}
Clustering of cardiovascular risk factors is thought to occur early in life. The endothelium is an important regulator of microvascular function. We investigated the relationship between microvascular function and cardiovascular risk factors in 145 normal, healthy children aged 11-14 years. Skin microvascular responses, measured using laser Doppler imaging, to iontophoresis of acetylcholine (ACh) and sodium nitroprusside (SNP), were negatively correlated with percentage body fat (r = -0.20, P… CONTINUE READING

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