Impaired metabolism of methionine in severe liver diseases I. Clinical and pathophysiological significance of elevated serum methionine levels

@article{Higashi1982ImpairedMO,
  title={Impaired metabolism of methionine in severe liver diseases I. Clinical and pathophysiological significance of elevated serum methionine levels},
  author={Toshihiro Higashi},
  journal={Gastroenterologia Japonica},
  year={1982},
  volume={17},
  pages={117-124}
}
Serum methionine levels increased to a greater extent in patients with severe liver diseases such as fulminant hepatitis and liver cirrhosis with and without hepatic encephalopathy. However, the concentrations remained unchanged in non-encephalopathic cirrhotic cases associated with hepatocellular carcinoma, and their serum methionine levels increased only moderately even at the time of encephalopathy. At least two different mechanisms of serum methionine elevations, possibly due to release… CONTINUE READING