Impaired learning and memory in CD38 null mutant mice

@inproceedings{Kim2016ImpairedLA,
  title={Impaired learning and memory in CD38 null mutant mice},
  author={Somi Kim and TaeHyun Kim and H Lee and E J Jang and Hyun-Hee Ryu and Minkyung Kang and So-Young Rah and Juyoun Yoo and Bolam Lee and Jae-Ick Kim and Chae Seok Lim and Sang Jeong Kim and U Kim and Yong-Seok Lee and Bong-Kiun Kaang},
  booktitle={Molecular Brain},
  year={2016}
}
CD38 is an enzyme that catalyzes the formation of cyclic ADP ribose and nicotinic acid adenine dinucleotide phosphate, both of which are involved in the mobilization of Ca2+ from intracellular stores. Recently, CD38 has been shown to regulate oxytocin release from hypothalamic neurons. Importantly, CD38 mutations are associated with autism spectrum disorders (ASD) and CD38 knockout (CD38−/−) mice display ASD-like behavioral phenotypes including deficient parental behavior and poor social… CONTINUE READING
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