Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I.

@article{CastillaCortazar1997ImpairedIS,
  title={Impaired intestinal sugar transport in cirrhotic rats: correction by low doses of insulin-like growth factor I.},
  author={Inma Castilla-Cortazar and Jes{\'u}s Prieto and Elena Urdaneta and Mar{\'i}a Soledad Pascual and Marina N{\'u}{\~n}ez and Enrique Zudaire and Mar{\'i}a Domingo Garcia and J. Quiroga and Santiago Santidri{\'a}n},
  journal={Gastroenterology},
  year={1997},
  volume={113 4},
  pages={1180-7}
}
BACKGROUND & AIMS Malnutrition is a complication of liver cirrhosis accompanied by reduced insulin-like growth factor I (IGF-I) availability. The aim of this study was to analyze the effect of IGF-I on intestinal D-galactose absorption in cirrhotic rats. METHODS IGF-I (2 micrograms.100 g body wt-1.day-1) or saline were given for 14 days to rats in whom cirrhosis was induced with CCl4. Galactose transport and sodium-glucose/galactose-ligand transporter 1 (SGLT-1) expression were assessed in… CONTINUE READING
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