Impaired inotropic responses to a-adrenergic stimulation in experimental left ventricular hypertrophy

@inproceedings{Fouad2005ImpairedIR,
  title={Impaired inotropic responses to a-adrenergic stimulation in experimental left ventricular hypertrophy},
  author={Fetnat M. Fouad and K Shimamatsu and M M Hanna and Philip A. Khairallah and Robert C. Tarazi},
  year={2005}
}
We have previously reported that left ventricular hypcrtrophy in two-kidney, one-clip renal hypertensive rats (2K-iC RHRs) was associated with dimiinished inotropic responsiveniess to isoproterenol and glucagon, suggesting an alteration in the receptor-adenylate cyclase cascade. The present study was perfornmed to investigate the hypothesis that in these… CONTINUE READING