Impaired heart rate response to graded exercise. Prognostic implications of chronotropic incompetence in the Framingham Heart Study.

@article{Lauer1996ImpairedHR,
  title={Impaired heart rate response to graded exercise. Prognostic implications of chronotropic incompetence in the Framingham Heart Study.},
  author={Michael S. Lauer and Peter M. Okin and Martin G. Larson and J. Colin Evans and Daniel L{\'e}vy},
  journal={Circulation},
  year={1996},
  volume={93 8},
  pages={1520-6}
}
BACKGROUND Previous reports have suggested that an attenuated exercise heart rate response may be associated with coronary heart disease risk and with mortality. These observations may parallel the association between reduced heart rate variability during normal activities and adverse outcome. This investigation was designed to look at the prognostic implications of exercise heart rate response in a population-based sample. METHODS AND RESULTS In this prospective cohort investigation, 1575… CONTINUE READING