Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation.

@article{Benavides2002ImpairedHF,
  title={Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation.},
  author={Fernando J. Benavides and Matthew F. Starost and M{\'o}nica Flores and Irma B. Gimenez-Conti and J. -L. Gu{\'e}net and Claudio J. Conti},
  journal={The American journal of pathology},
  year={2002},
  volume={161 2},
  pages={693-703}
}
We previously described an autosomal-recessive mutation named nackt (nkt) exhibiting partial alopecia associated with CD4(+) T-cell deficiency. Also, we recently reported that nkt (now Ctsl(nkt)) comprises a deletion in the cathepsin L (Ctsl) gene. Another recent study reported that Ctsl knockout mice have CD4(+) T-cell deficiency and periodic shedding of… CONTINUE READING