Impaired glucose tolerance is associated with increased islet amyloid polypeptide (IAPP) immunoreactivity in pancreatic beta cells.

@article{Johnson1989ImpairedGT,
  title={Impaired glucose tolerance is associated with increased islet amyloid polypeptide (IAPP) immunoreactivity in pancreatic beta cells.},
  author={Kenneth H. Johnson and Timothy O'Brien and King Jordan and Per Westermark},
  journal={The American journal of pathology},
  year={1989},
  volume={135 2},
  pages={
          245-50
        }
}
Adult cats determined by clinical laboratory evaluations to be normal, impaired glucose tolerant, or overtly diabetic were used to explore prospectively the relationships among pancreatic beta cell islet amyloid polypeptide (IAPP) immunoreactivity, islet amyloid (IA) deposition, and diabetogenesis. IAPP-derived IA was found in 11 of 14 (79%) diabetic cats, in four of nine (44%) impaired glucose tolerant cats, and in two of eight (25%) normal adult cats. The presence of IA even in very small… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 29 CITATIONS, ESTIMATED 48% COVERAGE

60 Citations

0510'90'96'03'10'17
Citations per Year
Semantic Scholar estimates that this publication has 60 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…