Impaired fMRI activation in patients with primary brain tumors

  title={Impaired fMRI activation in patients with primary brain tumors},
  author={Zhen Jiang and Alexandre Krainik and Olivier David and Caroline Salon and Ir{\`e}ne Tropr{\`e}s and Dominique Hoffmann and Nicolas Pannetier and Emmanuel Luc Barbier and Eduardo Ramos Bomb{\`i}n and Jan Warnking and Caroline Pasteris and Stefan Chabardes and François Berger and Sylvie Grand and Christoph Segebarth and Emmanuel Gay and Jean-François Le Bas},
To characterize peritumoral BOLD contrast disorders, 25 patients referred for resection of primary frontal or parietal neoplasms (low-grade glioma (LGG) (n=8); high-grade glioma (HGG) (n=7); meningioma (n=10)) without macroscopic tumoral infiltration of the primary sensorimotor cortex (SM1) were examined preoperatively using BOLD fMRI during simple motor tasks. Overall cerebral BOLD signal was estimated using vasoreactivity to carbogen inhalation. Using bolus of gadolinium, cerebral blood flow… CONTINUE READING


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