Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients.

Abstract

UNLABELLED Background Recent findings suggest that a specific deletion of Dicer1 in mesenchymal stromal cell-derived osteoprogenitors triggers several features of myelodysplastic syndrome in a murine model. Our aim was to analyze DICER1 and DROSHA gene and protein expression in mesenchymal stromal cells (the osteoblastic progenitors) obtained from bone… (More)
DOI: 10.3324/haematol.2011.054437

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@article{Santamaria2012ImpairedEO, title={Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients.}, author={Carlos Santamaria and Sandra Munti{\'o}n and Beatriz Ros{\'o}n and Bel{\'e}n Blanco and Olga L{\'o}pez-Villar and Soraya Carrancio and Ferm{\'i}n Mart{\'i}n S{\'a}nchez-Guijo and Mar{\'i}a D{\'i}ez-Campelo and Stela {\'A}lvarez-Fern{\'a}ndez and Mar{\'i}a Eugenia Sarasquete and Javier De Las Rivas and Marcos Gonzalez and Jes{\'u}s Fernando San Miguel and Mar{\'i}a Consuelo del Ca{\~n}izo}, journal={Haematologica}, year={2012}, volume={97 8}, pages={1218-24} }