Impaired endothelium independent vasodilation in the cutaneous microvasculature of young obese adults.

@article{Patik2016ImpairedEI,
  title={Impaired endothelium independent vasodilation in the cutaneous microvasculature of young obese adults.},
  author={Jordan C Patik and Kevin M. Christmas and Chansol Hurr and R Matthew Brothers},
  journal={Microvascular research},
  year={2016},
  volume={104},
  pages={63-8}
}
Microvascular dysfunction contributes to the development of cardiovascular and metabolic disease. This study tested the hypothesis that young obese (BMI>30 kg m(-2)), otherwise healthy, adults (N=15) have impaired microvascular function relative to age and sex matched, lean (BMI<25 kg m(-2)) individuals (N=14). Participants were instrumented with two microdialysis probes in the cutaneous vasculature of one forearm; one for a wide dose range of infusions of the endothelium-dependent vasodilator… CONTINUE READING