Impaired cortisol response to acute stressors in patients with coronary disease. Implications for inflammatory activity.

OBJECTIVES Inflammation is assumed to play a major role in the progress of atherosclerotic disease. We hypothesized that an altered hypothalamic-pituitary adrenal (HPA) axis activity was linked to a disinhibited inflammatory activity in patients with coronary artery disease (CAD). METHODS Thirty CAD patients were assessed 12-14 weeks after a first-time… CONTINUE READING