Impaired cholecystokinin secretion and disturbed appetite regulation in women with polycystic ovary syndrome

@article{LindnHirschberg2004ImpairedCS,
  title={Impaired cholecystokinin secretion and disturbed appetite regulation in women with polycystic ovary syndrome},
  author={Angelica Lind{\'e}n Hirschberg and Sabine Naess{\'e}n and Mats Stridsberg and Birgitta Bystr{\"o}m and Jan Gunnar Holte},
  journal={Gynecological Endocrinology},
  year={2004},
  volume={19},
  pages={79 - 87}
}
Increased amount of abdominal fat and obesity are common in polycystic ovary syndrome (PCOS). A higher prevalence of bulimia nervosa and greater cravings for sweets have also been reported in these patients. The present study aimed to compare meal-related appetite and secretion of the ‘satiety peptide’ cholecystokinin (CCK) and glucose regulatory hormones in PCOS women and controls. Sixteen pairs of women with PCOS and controls matched for age and body mass index participated in the study… 
Gastrointestinal hormone secretion in women with polycystic ovary syndrome: an observational study.
TLDR
Deficient secretion of GLP-1 and PYY does not contribute to excessive food intake in the pathophysiology of PCOS, and hormone responses to oral glucose rather than a physiological meal are examined.
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TLDR
The gastrointestinal hormones are highlighted, the potential strategies aimed at modifying hormones for treatment in PCOS are discussed, and the current non-pharmacologic management of body weight is hard to achieve.
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TLDR
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TLDR
The imbalance in the feedback mechanisms between insulin and ghrelin, present in obese women, especially those with IR, may affect food intake throughout the day and that could be a mechanism for the development of obesity in PCOS.
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TLDR
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TLDR
The results support the suggestion that androgens play a role in bulimic behavior and treatment with an antiandrogenic OC may serve as a new strategy for treatment of bulimia nervosa and particularly in those patients with hyper androgenic symptoms.
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TLDR
Basal and stimulated hunger and satiety hormones in lean PCOS patients are not different from lean healthy women, except for a lower meal-stimulated ghrelin response and short-term use of a low-dose oral contraceptive does not have an effect on appetite regulation of PCOS.
Neuroendocrine Regulation of Food Intake in Polycystic Ovary Syndrome
TLDR
Current knowledge about the neuroendocrine mechanisms underlying the interplay between feeding behavior, obesity, and reproductive abnormalities in PCOS is analyzed.
Polycystic ovary syndrome in bulimic women – an evaluation based on the new diagnostic criteria
TLDR
Increased occurrence of menstrual disturbances, hirsutism and PCOS in bulimic women, whereas ovarian variables and acne did not differ from controls, which may indicate increased androgen sensitivity in these women.
The Overlap Between Binge Eating Behaviors and Polycystic Ovarian Syndrome: An Etiological Integrative Model.
TLDR
It is suggested that an increased prevalence of binge eating has been reported in women with Polycystic Ovarian Syndrome; and that women suffering from BN and BED (Binge Eating Disorder) are more likely to display polycystic ovaries.
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