Impaired cardiac ischemic tolerance in spontaneously hypertensive rats is attenuated by adaptation to chronic and acute stress.

@article{Ravingerov2011ImpairedCI,
  title={Impaired cardiac ischemic tolerance in spontaneously hypertensive rats is attenuated by adaptation to chronic and acute stress.},
  author={T{\'a}ňa Ravingerov{\'a} and Iveta Bernatova and Jana Matej{\'i}kov{\'a} and Veronika Ledv{\'e}nyiov{\'a} and Martina Nem{\vc}ekov{\'a} and Olga Pechanova and Narcis Tribulova and J{\'a}n Slez{\'a}k},
  journal={Experimental and clinical cardiology},
  year={2011},
  volume={16 3},
  pages={e23-9}
}
Chronic hypertension may have a negative impact on the myocardial response to ischemia. On the other hand, intrinsic ischemic tolerance may persist even in the pathologically altered hearts of hypertensive animals, and may be modified by short- or long-term adaptation to different stressful conditions. The effects of long-term limitation of living space (ie, crowding stress [CS]) and brief ischemia-induced stress on cardiac response to ischemia/reperfusion (I/R) injury are not yet fully… CONTINUE READING