Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model.

Abstract

OBJECTIVE To establish a drill-hole defect model in osteoporotic mouse femur by comparing temporal cortical bone healing pattern between OVX-induced osteoporotic bone and sham-operated bone. METHODS 3-month-old female C57BL/6 mice were randomly divided into an ovariectomy group (OVX) and a sham-operated group (Sham). At 6 weeks post-surgery, 7 mice from… (More)
DOI: 10.1016/j.bone.2011.03.720

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@article{He2011ImpairedBH, title={Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model.}, author={Yi-xin He and Ge Zhang and Xiao-hua Pan and Zhong Liu and Li-zhen Zheng and Chun-Wai Chan and Kwong-man Lee and Yong-ping Cao and G. R. Li and Lei Wei and Leung-kim Hung and Kwok-Sui Leung and Ling Qin}, journal={Bone}, year={2011}, volume={48 6}, pages={1388-400} }