Impaired auditory and contextual fear conditioning in soman-exposed rats.

  title={Impaired auditory and contextual fear conditioning in soman-exposed rats.},
  author={Mark C Moffett and Mark K Schultz and Julia E Schwartz and Michael F Stone and Lucille A. Lumley},
  journal={Pharmacology, biochemistry, and behavior},
  volume={98 1},
Exposure to soman (GD) can result in prolonged seizures and subsequent neuropathology in a variety of brain regions including the amygdala and hippocampus. Both regions are believed to play important roles in the development and expression of fear conditioning. The purpose of this experiment was to test these conditioning tasks as a possible behavioral correlate of the observed neuropathology. Male rats were exposed to GD (1.0 or 1.2×LD50) or saline followed with injections of atropine sulfate… CONTINUE READING


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